Parkinson’s disease or PD is a degenerative disorder which affects the CNS (Central Nervous System) of elderly people. This disease leads to gradual deterioration and impairment of brain neurons. The exact region of the brain that is affected by Parkinson’s disease is called the substantia nigra.
Substantia nigra is responsible for the production of a brain chemical called dopamine. When the levels of the brain chemical dopamine plummet, due to the fast spreading Parkinson’s disease, it leads to impaired communication between the substantia nigra and corpus striatum.
The corpus striatum is composed of collection of nuclei called basal ganglia. Basal ganglia are responsible for controlling emotions, body functions and learning. So, any changes in the levels of the hormone dopamine ultimately affect the motor functions of the body.
Causes Of Parkinson’s Disease
Parkinson’s disease is a movement related disorder which is characterized by constant shaking, slowness or difficulty in moving, and body rigidity.
There are numerous factors which are responsible for the onset of this progressive degenerative disorder and few of the common causes behind Parkinson’s disease have been described below.
Individuals who carry a certain defective gene in their bodies are twice as likely to develop Parkinson’s disease as others.
Researchers argue that Parkinson’s disease is primarily a hereditary disease and individuals who have close family members afflicted by this disease are very likely to suffer from Parkinson’s disease or PD themselves.
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People who are suffering from mental disorders like paranoia or schizophrenia are prescribed antipsychotic drugs. Sustained usage of antipsychotic drugs over a long period of time can affect the specific region of the brain called the substantia nigra -which is responsible for producing the chemical dopamine.
When the levels of brain chemical dopamine drop it can lead to impaired communication between substantia nigra and corpus striatium. This reduced communication between the two important regions of the brain can ultimately affect the motor functions of the body.
Few people are even aware of the fact that constant exposure to harmful environmental toxins can lead to Parkinson’s disease. The receptor cells located deep inside the brain are destroyed slowly when our bodies are constantly exposed to harmful household and environmental chemical toxins.
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When these receptor cells die out, it affects the muscle motor functions of the body. The best way to combat pollutants which destroy the body cells is to eat a diet that is rich in vital antioxidants and drink at least 8 glasses of water every single day to flush the toxins from the system.
Shy Drager Syndrome
People who suffer from shy drager syndrome, a rare disorder which affects the autonomous nervous system, are very likely to develop Parkinson’s disease later on in their life.
The basal ganglia of the brain are badly damaged when a person suffers severe head trauma. One of the causative factors behind Parkinson’s disease are damaged basal ganglia.
People who abuse street drugs like synthetic heroin, MTPT are actually damaging the dopamine transmission and ultimately paving the way for the degenerative disease called PD.
Individuals who suffer massive strokes, which destroy a large part of their brain, are very likely to develop Parkinson’s disease.
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Blood Vessel Disorder
Blood vessel disorders like atherosclerosis can pave the way for Parkinsons disease, especially if adequate measures are not taken to rectify faulty blood vessels early on.